A Multicenter, Randomized, Double Double-Blind, Placebo Placebo-Controlled Trial of Nalbuphine ER Tablets for Uremic Pruritus
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چکیده
منابع مشابه
Kappa-opioid system in uremic pruritus: multicenter, randomized, double-blind, placebo-controlled clinical studies.
Uremic pruritus is a very common and frustrating condition for both patients and clinicians because no treatment has been demonstrated to be effective in relieving the itch. In this report, nalfurafine, a new kappa-opioid receptor agonist, was used to treat uremic pruritus in patients who were undergoing routine hemodialysis. Two multicenter, randomized, double-blind, placebo-controlled studies...
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31 Cerebrolysin and Recovery After Stroke (CARS;cerebrolysinと 脳卒中後の回復) ―無作為化プラセボ対照二重盲検多施設共同試験 Cerebrolysin and Recovery After Stroke (CARS) A Randomized, Placebo-Controlled, Double-Blind, Multicenter Trial Dafin F. Muresanu, MD, PhD 1 ; Wolf-Dieter Heiss, MD 2 ; Volker Hoemberg, MD 3 , et al. 1 Department of Clinical Neurosciences, “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Nap...
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Results: The cumulative number of gadoliniumenhancing MRI lesions during the first 6 months were similar in the -3 fatty acids and placebo groups (median difference, 1; 95% CI, 0 to 3; P=.09). No difference in relapse rate was detected after 6 (median difference, 0; 95% CI, 0 to 0; P=.54) or 24 (median difference, 0; 95% CI, 0 to 0; P=.72) months. The proportion of patients without disability p...
متن کاملA Randomized, Placebo-Controlled Double-Blind Trial
The efficacy and safety of pentoxifylline were assessed in 297 adult patients with ischemic stroke in a molticenter, doable-blind, randomized and placebo-controlled trial. Treatment was started within 12 hoars after the stroke onset Study medication was administered intravenously continuously (16 mg/kg/day, maximum 1,200 mg/day) for 3 days and per os (400 mg ti.d.) for the remainder of 28 days....
متن کاملA Randomized, Double-Blind, placebo-Controlled Trial
Method: Five hundred forty-two outpatients with bipolar I (N=360) or 11 (N=182) disorder experiencing a major depressive episode (DSM-IV) were randomly assigned to 8 weeks of quetiapine (600 or 300 mgl day) or placebo. The prima ry efficacy measure was mean change from base))ne to week 8 in the Montgomery-Asberg Depression Rating Scale total score. Additional efficacy assessments included the H...
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ژورنال
عنوان ژورنال: SKIN The Journal of Cutaneous Medicine
سال: 2021
ISSN: 2574-1624
DOI: 10.25251/skin.5.supp.28